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Pamela Clark
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Pamela Clark, CRNI, is a Nurse Supervisor for Accredo, a leader in specialty pharmacy care. She has more than 28 years of experience in infusion therapy and infusion education with both licensed nurses and patients. Her experience spans multiple infusion settings including: acute care, long-term care, home infusion, and ambulatory infusion care. She also has experience in oncology and oncology research.


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Transfusion Therapy in the Adult Patient

An online continuing education course for nurses, medical health care professionals, and other interested individuals.

This instructional course has been designed for nurses caring for the adult patient receiving transfusion therapy. There are various blood components infused for very specific purposes, and each component requires knowledge related to that specific product. This specialized type of therapy requires advanced nursing knowledge beyond that required for the provision of general infusion therapy. Therefore, education related specifically to the administration of blood products is crucial to the safe and effective use of these components. This course will provide information necessary for administering these life saving infusions.

State Boards of Nursing have varying positions on the role of the LPN/LVN in the administration of infusion therapy, including the administration of blood products. A link to each state board of nursing is listed here. Competency requirements are obtained and maintained through the nurse’s employer, facility or institution.


Upon completion of this course, the participant will be able to:
  1. Explain the blood grouping systems and their importance in transfusion therapy.
  2. List available blood components and indications for each.
  3. Describe the activities required in preparation for a transfusion.
  4. Identify equipment used to administer a transfusion and it’s proper usage.
  5. Describe the nursing management of a blood component infusion.
  6. Describe signs and symptoms of transfusion reactions, and appropriate interventions for each.
  7. Explain appropriate patient education related to transfusion therapy.
  8. Identify the required documentation for a blood transfusion.


Chapter 1
Introduction to Transfusion Therapy
  • Blood Components
  • ABO Blood Group System
  • Rh Blood Group System
  • Other Blood Group Antigens
  • HLA System
Chapter 2
Whole Blood
  • Description
  • Indications
Chapter 3
Packed Red Blood Cells
  • Description
  • Indications
  • Donation and Testing
  • Red Blood Cell Subsets 
Chapter 4
  • Description
  • Indications
  • Donation and Testing
  • Platelet Subsets
Chapter 5
  • Description
  • Indications
  • Donation and Testing
Chapter 6
  • Description
  • Indications
  • Donation and Testing
Chapter 7
Clotting Factors
  • Cryoprecipitate
  • Factor Concentrates
Chapter 8
Pre-transfusion Activities
  • Physician Order
  • Patient Consent
  • Type and Crossmatch
  • Vascular Access
  • Baseline Vital Signs
Chapter 9
Transfusion Administration
  • Component Transport and Storage
  • Equipment
  • Pre-medication
  • Identification
  • Administration
  • Monitoring
  • Patient Education
  • Documentation
Chapter 10
  • Immune Complications
    • Hemolytic Reactions
    • Non-Hemolytic Reactions
  • Non-immune Complications
    • Infectious Complications
    • Transfusion Associated Fluid Overload (TACO)
    • Complications of Massive Transfusion

Course Snapshot

Cost: $ 40.00
Contact Hours: 4


After successful completion the licensed nurse: RN, LPN/LVN will receive 4.0 contact hours.  Provider approved by the California Board of Registered Nursing, Provider # CEP 15467 and by the Florida Board of Nursing, CE Broker Tracking # is 20-315851.

RN, Nurse Practitioner, and Clinical Nurse Specialist will receive 4 contact hours. Provider approved by the District of Columbia Board of Nursing, CE Broker Tracking # is 20-315851.

This document must be retained by the licensee for a period of four years after the course concludes.

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